The MRC Protein Phosphorylation Unit pioneered analysis of the selectivity of protein kinase inhibitors by setting up one of the first services to tackle this problem in 1998. This procedure, termed “kinase profiling” proved to be of great help to the pharmaceutical industry, speeding up the development of specific protein kinase inhibitors with therapeutic potential. Many academic centres, including ourselves, have drug discovery programmes for protein kinases and need to access "kinase profiling" services. The Medical Research Council Strategy Board have provided the MRC Protein Phosphorylation Unit with funding to make the "kinase profiling" service widely available and to continue the expansion of the panel beyond 100 kinases over the next few years.